In this article, John Money and his colleagues expand upon prior medical guidance that focused on gonads as the primary mechanisms for marking sex.

They identify six factors to consider when "determining" someone's sex: assigned sex and sex of rearing, external genital morphology, internal reproductive structures, hormonal and secondary sex characteristics, gonadal sex, and chromosomal sex.

This and several other articles will come to be known as the "Hopkins protocols" for the medical "management" of intersex conditions.